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Structural Mechanisms Underlying Benzodiazepine Modulation of the GABA(A) Receptor
Many clinically important drugs target ligand-gated ion channels; however, the mechanisms by which these drugs modulate channel function remain elusive. Benzodiazepines (BZDs), anesthetics, and barbiturates exert their CNS actions by binding to GABA(A) receptors and modulating their function. The st...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Society for Neuroscience
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2410040/ https://ncbi.nlm.nih.gov/pubmed/18367615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5727-07.2008 |
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