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Structural Mechanisms Underlying Benzodiazepine Modulation of the GABA(A) Receptor

Many clinically important drugs target ligand-gated ion channels; however, the mechanisms by which these drugs modulate channel function remain elusive. Benzodiazepines (BZDs), anesthetics, and barbiturates exert their CNS actions by binding to GABA(A) receptors and modulating their function. The st...

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Detalhes bibliográficos
Main Authors: Hanson, Susan M., Czajkowski, Cynthia
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2410040/
https://ncbi.nlm.nih.gov/pubmed/18367615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5727-07.2008
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