טוען...
Different Residues in the GABA(A) Receptor Benzodiazepine Binding Pocket Mediate Benzodiazepine Efficacy and Binding
Benzodiazepines (BZDs) exert their therapeutic actions by binding to the GABA(A) receptor (GABA(A)R) and allosterically modulating GABA-induced chloride currents (I(GABA)). A variety of ligands with divergent structures bind to the BZD site, and the structural mechanisms that couple their binding to...
שמור ב:
| Main Authors: | , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
The American Society for Pharmacology and Experimental Therapeutics
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3127544/ https://ncbi.nlm.nih.gov/pubmed/21447642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.069542 |
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