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Multiple Tyrosine Residues Contribute to GABA Binding in the GABA(C) Receptor Binding Pocket
[Image: see text] The ligand binding site of Cys-loop receptors is dominated by aromatic amino acids. In GABA(C) receptors, these are predominantly tyrosine residues, with a number of other aromatic residues located in or close to the binding pocket. Here we examine the roles of these residues using...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3309607/ https://ncbi.nlm.nih.gov/pubmed/22448304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn200103n |
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