Different Benzodiazepines Bind with Distinct Binding Modes to GABA(A) Receptors

[Image: see text] Benzodiazepines are clinically relevant drugs that bind to GABA(A) neurotransmitter receptors at the α+/γ2– interfaces and thereby enhance GABA-induced chloride ion flux leading to neuronal hyperpolarization. However, the structural basis of benzodiazepine interactions with their h...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Elgarf, Alshaimaa A., Siebert, David C. B., Steudle, Friederike, Draxler, Angelika, Li, Guanguan, Huang, Shengming, Cook, James M., Ernst, Margot, Scholze, Petra
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102643/
https://ncbi.nlm.nih.gov/pubmed/29767950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00144
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados