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Different Benzodiazepines Bind with Distinct Binding Modes to GABA(A) Receptors
[Image: see text] Benzodiazepines are clinically relevant drugs that bind to GABA(A) neurotransmitter receptors at the α+/γ2– interfaces and thereby enhance GABA-induced chloride ion flux leading to neuronal hyperpolarization. However, the structural basis of benzodiazepine interactions with their h...
שמור ב:
| הוצא לאור ב: | ACS Chem Biol |
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| Main Authors: | , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Chemical
Society
2018
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| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6102643/ https://ncbi.nlm.nih.gov/pubmed/29767950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00144 |
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