טוען...
Rational Optimization of Diphenyl Ether Binding Kinetics to the Enoyl-ACP Reductase FabI1 from Burkholderia pseudomallei
There is growing awareness of the link between drug-target residence time and in vivo drug activity, and there are increasing efforts to determine the molecular factors that control the lifetime of a drug-target complex. Rational alterations in drug-target residence time require knowledge of both th...
שמור ב:
| הוצא לאור ב: | Biochemistry |
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| Main Authors: | , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5401771/ https://ncbi.nlm.nih.gov/pubmed/28225601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01048 |
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