Transient In Vivo Resistance Mechanisms of Burkholderia pseudomallei to Ceftazidime and Molecular Markers for Monitoring Treatment Response

le Cummings, Jason E., Slayden, Richard A.
Foilsithe in PLoS Negl Trop Dis (2017)

TPR1, a novel rifampicin derivative, demonstrates efficacy alone and in combination with doxycycline against the NIAID Category A priority pathogen Francisella tularensis

le Cummings, Jason E, Slayden, Keaton W, Slayden, Richard A
Foilsithe in JAC Antimicrob Resist (2021)

Mechanism and inhibition of the FabI enoyl-ACP reductase from Burkholderia pseudomallei

le Liu, Nina, Cummings, Jason E., England, Kathleen, Slayden, Richard A., Tonge, Peter J.
Foilsithe 2011

Formulation Studies of InhA inhibitors and Combination therapy to improve efficacy against Mycobacterium tuberculosis

le Knudson, Susan E., Cummings, Jason E., Bommineni, Gopal R., Pan, Pan, Tonge, Peter J., Slayden, Richard A.
Foilsithe in Tuberculosis (Edinb) (2016)

The Francisella tularensis FabI Enoyl-Acyl Carrier Protein Reductase Gene Is Essential to Bacterial Viability and Is Expressed during Infection

le Kingry, Luke C., Cummings, Jason E., Brookman, Kerry W., Bommineni, Gopal R., Tonge, Peter J., Slayden, Richard A.
Foilsithe 2013

Benzimidazole-Based Antibacterial Agents Against F. tularensis

le Kumar, Kunal, Awasthi, Divya, Lee, Seung-Yub, Cummings, Jason E., Knudson, Susan E., Slayden, Richard A., Ojima, Iwao
Foilsithe 2013

The Burkholderia pseudomallei Enoyl-Acyl Carrier Protein Reductase FabI1 Is Essential for In Vivo Growth and Is the Target of a Novel Chemotherapeutic with Efficacy

le Cummings, Jason E., Kingry, Luke C., Rholl, Drew A., Schweizer, Herbert P., Tonge, Peter J., Slayden, Richard A.
Foilsithe 2014

Manganese exposure in juvenile C57BL/6 mice increases glial inflammatory responses in the substantia nigra following infection with H1N1 influenza virus

le Bantle, Collin M., French, C. Tenley, Cummings, Jason E., Sadasivan, Shankar, Tran, Kevin, Slayden, Richard A., Smeyne, Richard J., Tjalkens, Ronald B.
Foilsithe in PLoS One (2021)

Thiolactomycin-based inhibitors of bacterial β-ketoacyl-ACP synthases with in vivo activity

le Bommineni, Gopal R., Kapilashrami, Kanishk, Cummings, Jason E., Lu, Yang, Knudson, Susan E., Gu, Chendi, Walker, Stephen G., Slayden, Richard A., Tonge, Peter J.
Foilsithe in J Med Chem (2016)

Immune Modulation as an Effective Adjunct Post-exposure Therapeutic for B. pseudomallei

le Wilson, William J., Afzali, Maryam F., Cummings, Jason E., Legare, Marie E., Tjalkens, Ronald B., Allen, Christopher P., Slayden, Richard A., Hanneman, William H.
Foilsithe in PLoS Negl Trop Dis (2016)

Rational Optimization of Diphenyl Ether Binding Kinetics to the Enoyl-ACP Reductase FabI1 from Burkholderia pseudomallei

le Neckles, Carla, Eltschkner, Sandra, Cummings, Jason E., Hirschbeck, Maria, Daryaee, Fereidoon, Bommineni, Gopal R., Zhang, Zhuo, Spagnuolo, Lauren, Yu, Weixuan, Davoodi, Shabnam, Slayden, Richard A., Kisker, Caroline, Tonge, Peter J.
Foilsithe in Biochemistry (2017)

Substituted Diphenyl Ethers as a Novel Chemotherapeutic Platform against Burkholderia pseudomallei

le Cummings, Jason E., Beaupre, Adam J., Knudson, Susan E., Liu, Nina, Yu, Weixuan, Neckles, Carla, Wang, Hui, Khanna, Avinash, Bommineni, Gopal R., Trunck, Lily A., Schweizer, Herbert P., Tonge, Peter J., Slayden, Richard A.
Foilsithe 2014

Rational Design of Broad Spectrum Antibacterial Activity Based on a Clinically Relevant Enoyl-Acyl Carrier Protein (ACP) Reductase Inhibitor

le Schiebel, Johannes, Chang, Andrew, Shah, Sonam, Lu, Yang, Liu, Li, Pan, Pan, Hirschbeck, Maria W., Tareilus, Mona, Eltschkner, Sandra, Yu, Weixuan, Cummings, Jason E., Knudson, Susan E., Bommineni, Gopal R., Walker, Stephen G., Slayden, Richard A., Sotriffer, Christoph A., Tonge, Peter J., Kisker, Caroline
Foilsithe 2014