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Mechanism and inhibition of the FabI enoyl-ACP reductase from Burkholderia pseudomallei

OBJECTIVES: As an initial step in developing novel antibacterials against Burkholderia pseudomallei, we have characterized the FabI enoyl-ACP reductase homologues in the type II fatty acid biosynthesis pathway from this organism and performed an initial enzyme inhibition study. METHODS: A BLAST anal...

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書誌詳細
主要な著者: Liu, Nina, Cummings, Jason E., England, Kathleen, Slayden, Richard A., Tonge, Peter J.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2011
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037155/
https://ncbi.nlm.nih.gov/pubmed/21393229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkq509
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