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Mechanism and inhibition of the FabI enoyl-ACP reductase from Burkholderia pseudomallei
OBJECTIVES: As an initial step in developing novel antibacterials against Burkholderia pseudomallei, we have characterized the FabI enoyl-ACP reductase homologues in the type II fatty acid biosynthesis pathway from this organism and performed an initial enzyme inhibition study. METHODS: A BLAST anal...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3037155/ https://ncbi.nlm.nih.gov/pubmed/21393229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkq509 |
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