Slow-Onset Inhibition of the FabI Enoyl Reductase from Francisella Tularensis: Residence Time and In Vivo Activity

Francisella tularensis is a highly virulent and contagious gram-negative intracellular bacterium that causes the disease tularemia in mammals. The high infectivity and the ability of the bacterium to survive for weeks in a cool, moist environment have raised the possibility that this organism could...

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Detalhes bibliográficos
Main Authors: Lu, Hao, England, Kathleen, Ende, Christopher am, Truglio, James J., Luckner, Sylvia, Reddy, B. Gopal, Marlenee, Nikki, Knudson, Susan E., Knudson, Dennis L., Bowen, Richard A., Kisker, Caroline, Slayden, Richard A., Tonge, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693246/
https://ncbi.nlm.nih.gov/pubmed/19206187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb800306y
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