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Mechanism and Inhibition of the FabV Enoyl-ACP Reductase from Burkholderia Mallei

Enoyl-ACP reductases catalyze the final step in the elongation cycle of the bacterial fatty acid biosynthesis (FAS-II) pathway. Currently four distinct enoyl-ACP reductases have been identified, which are the products of the fabI, fabL, fabK and fabV genes. The FabV enoyl-ACP reductase is the most r...

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Detalhes bibliográficos
Main Authors: Lu, Hao, Tonge, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892189/
https://ncbi.nlm.nih.gov/pubmed/20055482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi902001a
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