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Modeling Sex Differences in Pharmacokinetics, Pharmacodynamics, and Disease Progression Effects of Naproxen in Rats with Collagen-Induced Arthritis
Naproxen (NPX) is a frequently used nonsteroidal anti-inflammatory drug for rheumatoid arthritis (RA). Lack of quantitative information about the drug exposure–response relationship has resulted in empirical dosage regimens for use of NPX in RA. Few studies to date have included sex as a factor, alt...
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| Publicado no: | Drug Metab Dispos |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5399646/ https://ncbi.nlm.nih.gov/pubmed/28246127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.116.074526 |
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