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Modeling Sex Differences in Pharmacokinetics, Pharmacodynamics, and Disease Progression Effects of Naproxen in Rats with Collagen-Induced Arthritis
Naproxen (NPX) is a frequently used nonsteroidal anti-inflammatory drug for rheumatoid arthritis (RA). Lack of quantitative information about the drug exposure–response relationship has resulted in empirical dosage regimens for use of NPX in RA. Few studies to date have included sex as a factor, alt...
Kaydedildi:
| Yayımlandı: | Drug Metab Dispos |
|---|---|
| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The American Society for Pharmacology and Experimental Therapeutics
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5399646/ https://ncbi.nlm.nih.gov/pubmed/28246127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.116.074526 |
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