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The murine gene p27 (Kip1) is haplo-insufficient for tumour suppression
p27(Kip1) is a candidate human tumour-suppressor protein, because it is able to inhibit cyclin-dependent kinases and block cell proliferation(1-5). Abnormally low levels of the p27 protein are frequently found in human carcinomas, and these low levels correlate directly with both histological aggres...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5395202/ https://ncbi.nlm.nih.gov/pubmed/9823898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/24179 |
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