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Endocrine dysfunction in p27(Kip1) deficient mice and susceptibility to Wnt-1 driven breast cancer

The cyclin-dependent kinase (Cdk) inhibitor p27(Kip1) (p27) is a marker of prognosis in many cancers, including breast cancer. Low p27 expression correlates with poor prognosis, especially in hormone receptor positive breast tumors. This association suggests a role for p27 in hormone-dependent cance...

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Detalhes bibliográficos
Main Authors: Glover, Cynthia E., Gurley, Kay E., Kim, Kyung-Hoon, Storer, Barry, Fero, Mathew L., Kemp, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691144/
https://ncbi.nlm.nih.gov/pubmed/19380520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp089
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