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Effect of Xpcl1 Activation and p27(Kip1) Loss on Gene Expression in Murine Lymphoma

Mice lacking the p27(Kip1) Cdk inhibitor (Cdkn1b) exhibit increased susceptibility to lymphomas from the Maloney murine leukemia virus (M-MuLV), and exhibit a high frequency of viral integrations at Xpcl1 (Kis2), a locus on the X-chromosome. Xpcl1 encodes miR-106a∼363, a cluster of microRNAs that ar...

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Detalhes bibliográficos
Main Authors: Kuppers, Daniel A., Hwang, Harry C., Jackson, Aimee L., Linsley, Peter S., Clurman, Bruce E., Fero, Matthew L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055866/
https://ncbi.nlm.nih.gov/pubmed/21412408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014758
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