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Characterization and Targeted Disruption of Murine Nup50, a p27(Kip1)-Interacting Component of the Nuclear Pore Complex

p27(Kip1) is a member of the Cip-Kip family of cyclin-dependent kinase (Cdk) inhibitors that binds to cyclin-Cdk complexes and inhibits their catalytic activity in response to antiproliferative stimuli. p27(Kip1) is regulated by several posttranscriptional mechanisms, including subcellular localizat...

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Autors principals: Smitherman, Matthew, Lee, Keesook, Swanger, Jherek, Kapur, Raj, Clurman, Bruce E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC86029/
https://ncbi.nlm.nih.gov/pubmed/10891500
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