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Post-translational Activation of Glutamate Cysteine Ligase with Dimercaprol: A NOVEL MECHANISM OF INHIBITING NEUROINFLAMMATION IN VITRO

Neuroinflammation and oxidative stress are hallmarks of various neurological diseases. However, whether and how the redox processes control neuroinflammation is incompletely understood. We hypothesized that increasing cellular glutathione (GSH) levels would inhibit neuroinflammation. A series of thi...

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Pubblicato in:J Biol Chem
Autori principali: McElroy, Pallavi B., Sri Hari, Ashwini, Day, Brian J., Patel, Manisha
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392695/
https://ncbi.nlm.nih.gov/pubmed/28202547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.723700
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