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Post-translational Activation of Glutamate Cysteine Ligase with Dimercaprol: A NOVEL MECHANISM OF INHIBITING NEUROINFLAMMATION IN VITRO

Neuroinflammation and oxidative stress are hallmarks of various neurological diseases. However, whether and how the redox processes control neuroinflammation is incompletely understood. We hypothesized that increasing cellular glutathione (GSH) levels would inhibit neuroinflammation. A series of thi...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: McElroy, Pallavi B., Sri Hari, Ashwini, Day, Brian J., Patel, Manisha
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392695/
https://ncbi.nlm.nih.gov/pubmed/28202547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.723700
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