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Post-translational Activation of Glutamate Cysteine Ligase with Dimercaprol: A NOVEL MECHANISM OF INHIBITING NEUROINFLAMMATION IN VITRO

Neuroinflammation and oxidative stress are hallmarks of various neurological diseases. However, whether and how the redox processes control neuroinflammation is incompletely understood. We hypothesized that increasing cellular glutathione (GSH) levels would inhibit neuroinflammation. A series of thi...

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Publicado en:J Biol Chem
Main Authors: McElroy, Pallavi B., Sri Hari, Ashwini, Day, Brian J., Patel, Manisha
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392695/
https://ncbi.nlm.nih.gov/pubmed/28202547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.723700
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