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Enantioselective Synthesis of Oxetanes Bearing All-Carbon Quaternary Stereocenters via Iridium Catalyzed Alcohol-Vinyl Epoxide C-C Coupling()
Oxetanes bearing all-carbon quaternary stereocenters are readily prepared through the iridium catalyzed anti-diastereo- and enantioselective C-C coupling of primary alcohols and isoprene oxide. Based on this methodology, an oxetane containing analogue of haloperidol was prepared. A related azetidine...
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| Publicado no: | Chemistry |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5391976/ https://ncbi.nlm.nih.gov/pubmed/28039892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201606046 |
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