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Enantioselective Synthesis of Oxetanes Bearing All-Carbon Quaternary Stereocenters via Iridium Catalyzed Alcohol-Vinyl Epoxide C-C Coupling()

Oxetanes bearing all-carbon quaternary stereocenters are readily prepared through the iridium catalyzed anti-diastereo- and enantioselective C-C coupling of primary alcohols and isoprene oxide. Based on this methodology, an oxetane containing analogue of haloperidol was prepared. A related azetidine...

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Detaylı Bibliyografya
Yayımlandı:Chemistry
Asıl Yazarlar: Guo, Yi-An, Lee, Wonchul, Krische, Michael J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391976/
https://ncbi.nlm.nih.gov/pubmed/28039892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201606046
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