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Restriction of Human Cytomegalovirus Replication by ISG15, a Host Effector Regulated by cGAS-STING Double-Stranded-DNA Sensing

Accumulation of the interferon-stimulated gene 15 (ISG15) protein product, which is reversibly conjugated to numerous polypeptide targets, impacts the proteome and physiology of uninfected and infected cells. While many viruses, including human cytomegalovirus (HCMV), blunt host antiviral defenses b...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Bianco, Christopher, Mohr, Ian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391456/
https://ncbi.nlm.nih.gov/pubmed/28202760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02483-16
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