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Restriction of Human Cytomegalovirus Replication by ISG15, a Host Effector Regulated by cGAS-STING Double-Stranded-DNA Sensing

Accumulation of the interferon-stimulated gene 15 (ISG15) protein product, which is reversibly conjugated to numerous polypeptide targets, impacts the proteome and physiology of uninfected and infected cells. While many viruses, including human cytomegalovirus (HCMV), blunt host antiviral defenses b...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Bianco, Christopher, Mohr, Ian
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391456/
https://ncbi.nlm.nih.gov/pubmed/28202760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02483-16
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