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The binding orientation of epibatidine at α7 nACh receptors

Epibatidine is an alkaloid toxin that binds with high affinity to nicotinic and muscarinic acetylcholine receptors, and has been extensively used as a research tool. To examine binding interactions at the nicotinic receptor, it has been co-crystallised with the structural homologue acetylcholine bin...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Thompson, Andrew J., Metzger, Simon, Lochner, Martin, Ruepp, Marc-David
Formato: Artigo
Idioma:Inglês
Publicado em: Pergamon Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390772/
https://ncbi.nlm.nih.gov/pubmed/28089847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2017.01.008
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