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The binding orientation of epibatidine at α7 nACh receptors

Epibatidine is an alkaloid toxin that binds with high affinity to nicotinic and muscarinic acetylcholine receptors, and has been extensively used as a research tool. To examine binding interactions at the nicotinic receptor, it has been co-crystallised with the structural homologue acetylcholine bin...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Neuropharmacology
Päätekijät: Thompson, Andrew J., Metzger, Simon, Lochner, Martin, Ruepp, Marc-David
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Pergamon Press 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390772/
https://ncbi.nlm.nih.gov/pubmed/28089847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2017.01.008
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