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The binding orientation of epibatidine at α7 nACh receptors

Epibatidine is an alkaloid toxin that binds with high affinity to nicotinic and muscarinic acetylcholine receptors, and has been extensively used as a research tool. To examine binding interactions at the nicotinic receptor, it has been co-crystallised with the structural homologue acetylcholine bin...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Neuropharmacology
Main Authors: Thompson, Andrew J., Metzger, Simon, Lochner, Martin, Ruepp, Marc-David
Format: Artigo
Jezik:Inglês
Izdano: Pergamon Press 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390772/
https://ncbi.nlm.nih.gov/pubmed/28089847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2017.01.008
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