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The binding orientation of epibatidine at α7 nACh receptors

Epibatidine is an alkaloid toxin that binds with high affinity to nicotinic and muscarinic acetylcholine receptors, and has been extensively used as a research tool. To examine binding interactions at the nicotinic receptor, it has been co-crystallised with the structural homologue acetylcholine bin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neuropharmacology
Hauptverfasser: Thompson, Andrew J., Metzger, Simon, Lochner, Martin, Ruepp, Marc-David
Format: Artigo
Sprache:Inglês
Veröffentlicht: Pergamon Press 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390772/
https://ncbi.nlm.nih.gov/pubmed/28089847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2017.01.008
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