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The binding orientation of epibatidine at α7 nACh receptors

Epibatidine is an alkaloid toxin that binds with high affinity to nicotinic and muscarinic acetylcholine receptors, and has been extensively used as a research tool. To examine binding interactions at the nicotinic receptor, it has been co-crystallised with the structural homologue acetylcholine bin...

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Detaylı Bibliyografya
Yayımlandı:Neuropharmacology
Asıl Yazarlar: Thompson, Andrew J., Metzger, Simon, Lochner, Martin, Ruepp, Marc-David
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Pergamon Press 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390772/
https://ncbi.nlm.nih.gov/pubmed/28089847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2017.01.008
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