Phenotypic Screening Identifies Modulators of Amyloid Precursor Protein Processing in Human Stem Cell Models of Alzheimer’s Disease

Human stem cell models have the potential to provide platforms for phenotypic screens to identify candidate treatments and cellular pathways involved in the pathogenesis of neurodegenerative disorders. Amyloid precursor protein (APP) processing and the accumulation of APP-derived amyloid β (Aβ) pept...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Stem Cell Reports
Hauptverfasser: Brownjohn, Philip W., Smith, James, Portelius, Erik, Serneels, Lutgarde, Kvartsberg, Hlin, De Strooper, Bart, Blennow, Kaj, Zetterberg, Henrik, Livesey, Frederick J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2017
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390098/
https://ncbi.nlm.nih.gov/pubmed/28285880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.02.006
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge