The intact postsynaptic protein neurogranin is reduced in brain tissue from patients with familial and sporadic Alzheimer’s disease

Synaptic degeneration and neuronal loss are early events in Alzheimer’s disease (AD), occurring long before symptom onset, thus making synaptic biomarkers relevant for enabling early diagnosis. The postsynaptic protein neurogranin (Ng) is a cerebrospinal fluid (CSF) biomarker for AD, also in the pro...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol
Main Authors: Kvartsberg, Hlin, Lashley, Tammaryn, Murray, Christina E., Brinkmalm, Gunnar, Cullen, Nicholas C., Höglund, Kina, Zetterberg, Henrik, Blennow, Kaj, Portelius, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338696/
https://ncbi.nlm.nih.gov/pubmed/30244311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-018-1910-3
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