Neurogranin and YKL-40: independent markers of synaptic degeneration and neuroinflammation in Alzheimer’s disease

INTRODUCTION: Neuroinflammation and synaptic degeneration are major neuropathological hallmarks in Alzheimer’s disease (AD). Neurogranin and YKL-40 in cerebrospinal fluid (CSF) are newly discovered markers indicating synaptic damage and microglial activation, respectively. METHODS: CSF samples from...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Hellwig, Konstantin, Kvartsberg, Hlin, Portelius, Erik, Andreasson, Ulf, Oberstein, Timo Jan, Lewczuk, Piotr, Blennow, Kaj, Kornhuber, Johannes, Maler, Juan Manuel, Zetterberg, Henrik, Spitzer, Philipp
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690296/
https://ncbi.nlm.nih.gov/pubmed/26698298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-015-0161-y
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