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Alzheimer-associated cerebrospinal fluid fragments of neurogranin are generated by Calpain-1 and prolyl endopeptidase
BACKGROUND: Neurogranin (Ng) is a small 7.6 kDa postsynaptic protein that has been detected at elevated concentrations in cerebrospinal fluid (CSF) of patients with Alzheimer’s disease (AD), both as a full-length molecule and as fragments from its C-terminal half. Ng is involved in postsynaptic calc...
Zapisane w:
Wydane w: | Mol Neurodegener |
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Główni autorzy: | , , , , , , , , , , , |
Format: | Artigo |
Język: | Inglês |
Wydane: |
BioMed Central
2018
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6116393/ https://ncbi.nlm.nih.gov/pubmed/30157938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-018-0279-z |
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