Single-cell profiling reveals that eRNA accumulation at enhancer–promoter loops is not required to sustain transcription

Enhancers are intergenic DNA elements that regulate the transcription of target genes in response to signaling pathways by interacting with promoters over large genomic distances. Recent studies have revealed that enhancers are bi-directionally transcribed into enhancer RNAs (eRNAs). Using single-mo...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Rahman, Samir, Zorca, Cornelia E., Traboulsi, Tatiana, Noutahi, Emmanuel, Krause, Matthew R., Mader, Sylvie, Zenklusen, Daniel
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2017
Предметы:
Gene regulation, Chromatin and Epigenetics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389544/
https://ncbi.nlm.nih.gov/pubmed/27932455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1220
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы