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R-loops do not accumulate in transcription-defective hpr1-101 mutants: implications for the functional role of THO/TREX

To get further insight into the effect that THO/TREX and R-loops have in transcription-associated recombination and transcription, we analyzed the ability to form R-loops of hpr1-101, a THO mutation that impairs transcription and mRNP biogenesis without triggering hyper-recombination. Human AID, a c...

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Detalhes bibliográficos
Main Authors: Gómez-González, Belén, Aguilera, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715242/
https://ncbi.nlm.nih.gov/pubmed/19451165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp385
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