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R-loops do not accumulate in transcription-defective hpr1-101 mutants: implications for the functional role of THO/TREX
To get further insight into the effect that THO/TREX and R-loops have in transcription-associated recombination and transcription, we analyzed the ability to form R-loops of hpr1-101, a THO mutation that impairs transcription and mRNP biogenesis without triggering hyper-recombination. Human AID, a c...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2715242/ https://ncbi.nlm.nih.gov/pubmed/19451165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp385 |
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