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The S-Phase Checkpoint Is Required To Respond to R-Loops Accumulated in THO Mutants

Cotranscriptional R-loops are formed in yeast mutants of the THO complex, which functions at the interface between transcription and mRNA export. Despite the relevance of R-loops in transcription-associated recombination, the mechanisms by which they trigger recombination are still elusive. In order...

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Detalhes bibliográficos
Main Authors: Gómez-González, Belén, Felipe-Abrio, Irene, Aguilera, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747986/
https://ncbi.nlm.nih.gov/pubmed/19651896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00402-09
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