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Single-cell profiling reveals that eRNA accumulation at enhancer–promoter loops is not required to sustain transcription

Enhancers are intergenic DNA elements that regulate the transcription of target genes in response to signaling pathways by interacting with promoters over large genomic distances. Recent studies have revealed that enhancers are bi-directionally transcribed into enhancer RNAs (eRNAs). Using single-mo...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Rahman, Samir, Zorca, Cornelia E., Traboulsi, Tatiana, Noutahi, Emmanuel, Krause, Matthew R., Mader, Sylvie, Zenklusen, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389544/
https://ncbi.nlm.nih.gov/pubmed/27932455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1220
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