Mutations Conferring Resistance to Human Immunodeficiency Virus Type 1 Fusion Inhibitors Are Restricted by gp41 and Rev-Responsive Element Functions

One of the human immunodeficiency virus (HIV) envelope proteins, gp41, plays a key role in HIV fusion. A gp41-derived peptide, T-20, efficiently inhibits HIV fusion and is currently approved for treatment of HIV-infected individuals. Although resistant variants have been reported, the mechanism of t...

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Detalhes bibliográficos
Main Authors: Nameki, Daisuke, Kodama, Eiichi, Ikeuchi, Mieko, Mabuchi, Naoto, Otaka, Akira, Tamamura, Hirokazu, Ohno, Mutsuhito, Fujii, Nobutaka, Matsuoka, Masao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538534/
https://ncbi.nlm.nih.gov/pubmed/15613304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.764-770.2005
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