Dual inhibiting OCT4 and AKT potently suppresses the propagation of human cancer cells

AKT serves as an epigenetic modulator that links epigenetic regulation to cell survival and proliferation while the epigenetic mediator OCT4 critically controls stem cell pluripotency and self-renewal. Emerging evidence indicated their complicated interplays in cancer cells and cancer stem cells (CS...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Li, Wenxin, Zhou, Yanwen, Zhang, Xiaoqian, Yang, Ying, Dan, Songsong, Su, Tong, She, Shiqi, Dong, Weilai, Zhao, Qingwei, Jia, Jia, Yao, Hangping, Zheng, Min, Kang, Bo, Wang, Ying-Jie
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382782/
https://ncbi.nlm.nih.gov/pubmed/28383051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46246
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