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Dual inhibiting OCT4 and AKT potently suppresses the propagation of human cancer cells
AKT serves as an epigenetic modulator that links epigenetic regulation to cell survival and proliferation while the epigenetic mediator OCT4 critically controls stem cell pluripotency and self-renewal. Emerging evidence indicated their complicated interplays in cancer cells and cancer stem cells (CS...
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| Publicado en: | Sci Rep |
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| Autores principales: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5382782/ https://ncbi.nlm.nih.gov/pubmed/28383051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46246 |
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