Dual inhibiting OCT4 and AKT potently suppresses the propagation of human cancer cells

AKT serves as an epigenetic modulator that links epigenetic regulation to cell survival and proliferation while the epigenetic mediator OCT4 critically controls stem cell pluripotency and self-renewal. Emerging evidence indicated their complicated interplays in cancer cells and cancer stem cells (CS...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Li, Wenxin, Zhou, Yanwen, Zhang, Xiaoqian, Yang, Ying, Dan, Songsong, Su, Tong, She, Shiqi, Dong, Weilai, Zhao, Qingwei, Jia, Jia, Yao, Hangping, Zheng, Min, Kang, Bo, Wang, Ying-Jie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382782/
https://ncbi.nlm.nih.gov/pubmed/28383051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46246
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