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Dual inhibiting OCT4 and AKT potently suppresses the propagation of human cancer cells
AKT serves as an epigenetic modulator that links epigenetic regulation to cell survival and proliferation while the epigenetic mediator OCT4 critically controls stem cell pluripotency and self-renewal. Emerging evidence indicated their complicated interplays in cancer cells and cancer stem cells (CS...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5382782/ https://ncbi.nlm.nih.gov/pubmed/28383051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46246 |
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