Chemosensitivity of IDH1-mutated gliomas due to an impairment in PARP1-mediated DNA repair

Mutations in isocitrate dehydrogenase (IDH) are the most prevalent genetic abnormalities in lower grade gliomas. The presence of these mutations in glioma is prognostic for better clinical outcomes with longer patient survival. In the present study, we found that defects in oxidative metabolism and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Res
Egile Nagusiak: Lu, Yanxin, Kwintkiewicz, Jakub, Liu, Yang, Tech, Katherine, Frady, Lauren N., Su, Yu-Ting, Bautista, Wendy, Moon, Seog In, MacDonald, Jeffrey, Ewend, Matthew G., Gilbert, Mark R., Yang, Chunzhang, Wu, Jing
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380481/
https://ncbi.nlm.nih.gov/pubmed/28202508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-2773
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak