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VEGF165-induced vascular permeability requires NRP1 for ABL-mediated SRC family kinase activation
The vascular endothelial growth factor (VEGF) isoform VEGF165 stimulates vascular growth and hyperpermeability. Whereas blood vessel growth is essential to sustain organ health, chronic hyperpermeability causes damaging tissue edema. By combining in vivo and tissue culture models, we show here that...
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| 出版年: | J Exp Med |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5379968/ https://ncbi.nlm.nih.gov/pubmed/28289053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160311 |
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