VEGF165-induced vascular permeability requires NRP1 for ABL-mediated SRC family kinase activation

The vascular endothelial growth factor (VEGF) isoform VEGF165 stimulates vascular growth and hyperpermeability. Whereas blood vessel growth is essential to sustain organ health, chronic hyperpermeability causes damaging tissue edema. By combining in vivo and tissue culture models, we show here that...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Fantin, Alessandro, Lampropoulou, Anastasia, Senatore, Valentina, Brash, James T., Prahst, Claudia, Lange, Clemens A., Liyanage, Sidath E., Raimondi, Claudio, Bainbridge, James W., Augustin, Hellmut G., Ruhrberg, Christiana
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379968/
https://ncbi.nlm.nih.gov/pubmed/28289053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160311
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