VEGF165-induced vascular permeability requires NRP1 for ABL-mediated SRC family kinase activation

The vascular endothelial growth factor (VEGF) isoform VEGF165 stimulates vascular growth and hyperpermeability. Whereas blood vessel growth is essential to sustain organ health, chronic hyperpermeability causes damaging tissue edema. By combining in vivo and tissue culture models, we show here that...

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Опубликовано в: :J Exp Med
Главные авторы: Fantin, Alessandro, Lampropoulou, Anastasia, Senatore, Valentina, Brash, James T., Prahst, Claudia, Lange, Clemens A., Liyanage, Sidath E., Raimondi, Claudio, Bainbridge, James W., Augustin, Hellmut G., Ruhrberg, Christiana
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2017
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379968/
https://ncbi.nlm.nih.gov/pubmed/28289053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160311
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