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NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells

Sprouting blood vessels are led by filopodia-studded endothelial tip cells that respond to angiogenic signals. Mosaic lineage tracing previously revealed that NRP1 is essential for tip cell function, although its mechanistic role in tip cells remains poorly defined. Here, we show that NRP1 is dispen...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Rep
Egile Nagusiak: Fantin, Alessandro, Lampropoulou, Anastasia, Gestri, Gaia, Raimondi, Claudio, Senatore, Valentina, Zachary, Ian, Ruhrberg, Christiana
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cell Press 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528263/
https://ncbi.nlm.nih.gov/pubmed/26051942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.05.018
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