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NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells

Sprouting blood vessels are led by filopodia-studded endothelial tip cells that respond to angiogenic signals. Mosaic lineage tracing previously revealed that NRP1 is essential for tip cell function, although its mechanistic role in tip cells remains poorly defined. Here, we show that NRP1 is dispen...

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Detaylı Bibliyografya
Yayımlandı:Cell Rep
Asıl Yazarlar: Fantin, Alessandro, Lampropoulou, Anastasia, Gestri, Gaia, Raimondi, Claudio, Senatore, Valentina, Zachary, Ian, Ruhrberg, Christiana
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cell Press 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528263/
https://ncbi.nlm.nih.gov/pubmed/26051942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.05.018
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