Cargando...

NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells

Sprouting blood vessels are led by filopodia-studded endothelial tip cells that respond to angiogenic signals. Mosaic lineage tracing previously revealed that NRP1 is essential for tip cell function, although its mechanistic role in tip cells remains poorly defined. Here, we show that NRP1 is dispen...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Cell Rep
Main Authors: Fantin, Alessandro, Lampropoulou, Anastasia, Gestri, Gaia, Raimondi, Claudio, Senatore, Valentina, Zachary, Ian, Ruhrberg, Christiana
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528263/
https://ncbi.nlm.nih.gov/pubmed/26051942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.05.018
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!