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VEGF(189) binds NRP1 and is sufficient for VEGF/NRP1-dependent neuronal patterning in the developing brain
The vascular endothelial growth factor (VEGFA, VEGF) regulates neurovascular patterning. Alternative splicing of the Vegfa gene gives rise to three major isoforms termed VEGF(121), VEGF(165) and VEGF(189). VEGF(165) binds the transmembrane protein neuropilin 1 (NRP1) and promotes the migration, surv...
Gespeichert in:
| Veröffentlicht in: | Development |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Company of Biologists
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4302834/ https://ncbi.nlm.nih.gov/pubmed/25519242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.115998 |
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