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Imatinib may be ABL to improve anti-angiogenic therapy
We recently reported that neuropilin 1 (NRP1) drives angiogenesis by promoting extracellular matrix signaling in endothelial cells via ABL1 kinase. Imatinib targets this pathway in pathological angiogenesis and may provide a novel opportunity for anti-angiogenic therapy of age-related macular degene...
Tallennettuna:
| Julkaisussa: | Mol Cell Oncol |
|---|---|
| Päätekijät: | , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Taylor & Francis
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4905228/ https://ncbi.nlm.nih.gov/pubmed/27308396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.968034 |
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