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Probing the conformation of a conserved glutamic acid within the Cl(−) pathway of a CLC H(+)/Cl(−) exchanger

The CLC proteins form a broad family of anion-selective transport proteins that includes both channels and exchangers. Despite extensive structural, functional, and computational studies, the transport mechanism of the CLC exchangers remains poorly understood. Several transport models have been prop...

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Detalhes bibliográficos
Publicado no:J Gen Physiol
Main Authors: Vien, Malvin, Basilio, Daniel, Leisle, Lilia, Accardi, Alessio
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379918/
https://ncbi.nlm.nih.gov/pubmed/28246117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201611682
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