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Common Gating of Both CLC Transporter Subunits Underlies Voltage-dependent Activation of the 2Cl(−)/1H(+) Exchanger ClC-7/Ostm1
CLC anion transporters form dimers that function either as Cl(−) channels or as electrogenic Cl(−)/H(+) exchangers. CLC channels display two different types of “gates,” “protopore” gates that open and close the two pores of a CLC dimer independently of each other and common gates that act on both po...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3789960/ https://ncbi.nlm.nih.gov/pubmed/23983121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.509364 |
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