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Probing the conformation of a conserved glutamic acid within the Cl(−) pathway of a CLC H(+)/Cl(−) exchanger

The CLC proteins form a broad family of anion-selective transport proteins that includes both channels and exchangers. Despite extensive structural, functional, and computational studies, the transport mechanism of the CLC exchangers remains poorly understood. Several transport models have been prop...

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Publicat a:J Gen Physiol
Autors principals: Vien, Malvin, Basilio, Daniel, Leisle, Lilia, Accardi, Alessio
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379918/
https://ncbi.nlm.nih.gov/pubmed/28246117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201611682
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