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Probing the conformation of a conserved glutamic acid within the Cl(−) pathway of a CLC H(+)/Cl(−) exchanger

The CLC proteins form a broad family of anion-selective transport proteins that includes both channels and exchangers. Despite extensive structural, functional, and computational studies, the transport mechanism of the CLC exchangers remains poorly understood. Several transport models have been prop...

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Vydáno v:J Gen Physiol
Hlavní autoři: Vien, Malvin, Basilio, Daniel, Leisle, Lilia, Accardi, Alessio
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379918/
https://ncbi.nlm.nih.gov/pubmed/28246117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201611682
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