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Probing the conformation of a conserved glutamic acid within the Cl(−) pathway of a CLC H(+)/Cl(−) exchanger

The CLC proteins form a broad family of anion-selective transport proteins that includes both channels and exchangers. Despite extensive structural, functional, and computational studies, the transport mechanism of the CLC exchangers remains poorly understood. Several transport models have been prop...

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Bibliografiska uppgifter
I publikationen:J Gen Physiol
Huvudupphovsmän: Vien, Malvin, Basilio, Daniel, Leisle, Lilia, Accardi, Alessio
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379918/
https://ncbi.nlm.nih.gov/pubmed/28246117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201611682
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