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Developing Therapeutics for PrP Prion Diseases
The prototypical PrP prion diseases are invariably fatal, and the search for agents to treat them spans more than 30 years, with limited success. However, in the last few years, the application of high-throughput screening, medicinal chemistry, and pharmacokinetic optimization has led to important a...
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| Pubblicato in: | Cold Spring Harb Perspect Med |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5378016/ https://ncbi.nlm.nih.gov/pubmed/28096242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a023747 |
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