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Developing Therapeutics for PrP Prion Diseases

The prototypical PrP prion diseases are invariably fatal, and the search for agents to treat them spans more than 30 years, with limited success. However, in the last few years, the application of high-throughput screening, medicinal chemistry, and pharmacokinetic optimization has led to important a...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Cold Spring Harb Perspect Med
Päätekijät: Giles, Kurt, Olson, Steven H., Prusiner, Stanley B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378016/
https://ncbi.nlm.nih.gov/pubmed/28096242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a023747
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