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Developing Therapeutics for PrP Prion Diseases

The prototypical PrP prion diseases are invariably fatal, and the search for agents to treat them spans more than 30 years, with limited success. However, in the last few years, the application of high-throughput screening, medicinal chemistry, and pharmacokinetic optimization has led to important a...

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Bibliografski detalji
Izdano u:Cold Spring Harb Perspect Med
Glavni autori: Giles, Kurt, Olson, Steven H., Prusiner, Stanley B.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378016/
https://ncbi.nlm.nih.gov/pubmed/28096242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a023747
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